i dont know if i shoudl post this as it can be used to compromise network security by removing all local passwords. if this is used on any workstation that you do not have permission to doso on then i cannot be held responsible for any actions caused by useing it.
first if the disk is Fat32 (most are unless converted on install) then use a win 98 boot disk to geto the command prompt then locate this folder C:\WINDOWS\system32\config\
just incase you dont know DOS commands (im not sure on how computer savy you are so ill list them incase
c: [enter]
cd.. [enter] till just c:\ is displaing
cd windows[enter]
cd system32[enter]
cd config [enter]
now you should have a blank screen with this on c:\windows\system32\config
now type
del sam [enter]
when it asks you if your sure press y followed by enter
boot into windows and type in administrator as username then leave passoword blank press ok
the procedure is the same if its an NTFS disk but you will need a bootdisk with NTFS dos on avalable from
www.bootdisks.com
now you have admin rights therfore having the run of the pc.
i must stress that you must only do this on workstations you have permission for as it can get you in alot of trouble if you dont have permision to do this
EDIT: after a quick google serch i found this i think tis what i jus sed exept more detailed and a slightly differetn way
http://home.eunet.no/~pnordahl/ntpasswd/bootdisk.html