[JC]

Certain diseases will make you fat and there isnt too much you can do about that. Diabetes can do that, although there is some debate as to whether diabetes causes obesity or obesity causes diabetes. Having
defects in your LDL receptor wont help you lose wieght either and if you have Leptin receptor inactivity you are going to blow up to the size of a whale. On the whole though most fat people dont have these problems.