If you like funky hip-hop jazz kinda thing then DEFINATELY see Mr. Scruff
(I'm going to his residency night in Manchester on saturday)
Oh and DJ Yoda.
Obviously Chemical Brothers.
I really like Modest Mouse as well.
Altho you don't like Ska, Madness would be pretty good.
There are a load of others that you'll already know to see - Arctic Monkeys, Manics, Killers etc etc.